5 edition of Oxygen sensing in tissues found in the catalog.
Includes bibliographies and index.
|Statement||Helmut Acker, editor.|
|Contributions||Acker, H. 1939-|
|LC Classifications||QP177 .O96 1988|
|The Physical Object|
|Pagination||xii, 215 p. :|
|Number of Pages||215|
|LC Control Number||88012302|
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy. This book evaluates the various mediators that have been proposed, including the mitochondria, NAD(P)H oxidases, cytochrome p enzymes, and direct effects on enzymes. For example, many creatures use red blood cells to transport oxygen to tissues deep within their bodies. When its concentration sags, the body generates the hormone erythropoietin, which boosts red blood-cell production. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.
“How oxygen is sensed by both normal tissues and tumors is an incredibly important discovery that is highly deserving of a Nobel Prize,” says Amato Giaccia, a . This volume presents all aspects of delivery of oxygen to tissues and tumors in peer reviewed short articles. Both overview and the most recent, advanced techniques for oxygen measurement are presented. Articles and peer reviewers include those from leaders in their field.
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy. This book evaluates t. The physiology or medicine Nobel prize has been awarded to the scientist trio that uncovered how cells sense and adapt to changing oxygen levels. William Kaelin from Harvard University.
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Oxygen Sensing in Tissues [Acker, Helmut] on *FREE* shipping on qualifying offers. Oxygen Sensing in Tissues2/5(1).
Effect of Hypoxia on Ca 2+ Influx and Catecholamine Synthesis in Chemosensitive Cells of the Carotid Body in Tissue Culture.
Changes of the Bioelectrical Activity and Extracellular Micromilieu in the Central Nervous System During Variations of Local Oxygen Pressure Pages Speckmann, E.-J.
(et al.). Oxygen Sensing: Molecule to Man (Advances in Experimental Medicine and Biology) Softcover reprint of the original 1st ed. Edition in the expansion to include the study and discussion of oxygen sensing in other tissues and cells, and the genes involved. Bringing together scientists from cellular and systemic boundaries of physiology Format: Paperback.
About this book Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy.
The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes.
This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing Book Edition: 1. Sensing of tissue oxygen pressure is critical to homeostatic regulation of oxygen supply and many other adaptive changes in the cellular environment.
For example, there are many different biochemical and physiological mechanisms for regulating blood flow to each tissue and distributing the flow within the tissue according to the tissue by: 5.
Particle Oxygen Sensors for Magnetic Resonance Techniques. Oxygen-sensing NMR contrast agents are usually introduced into systemic circulation or directly injected into the tissue being measured. In order for the contrast agents to accumulate at a specific tissue location, contrast agents have been incorporated into nanoparticles and emulsions to create biocompatible, targeted delivery formulations.
A growing number of physiologically relevant genes are regulated in response to changes in intracellular oxygen tension. It is likely that cells from a wide variety of tissues share a common mechanism of oxygen sensing and signal transduction leading to the activation of the transcription factor hypoxia-inducible factor 1 (HIF-1).Cited by: Haemoglobin exists in two forms: taut (T), which has a low affinity for oxygen; and relaxed (R), which has a high affinity for oxygen.
The taut form predominates in the tissues (a high carbon dioxide, low pH environment) promoting oxygen release, whereas the relaxed form binds oxygen more avidly in areas of high pH, low carbon dioxide tension, and high partial pressures of oxygen Cited by: Oxygen Sensing in Tissues by Helmut Acker,Springer edition, paperback.
Quantification of tissue oxygen partial pressure (pO 2) at the skin surface is crucial for diagnostic applications in burns, reconstructive surgeries, diabetic ulcers, r, current advances in wearable and communications technologies have widened the use of transcutaneous oxygen monitors (TCOM) for home care or even enhance athletic : Emmanuel Roussakis, Juan Pedro Cascales, Haley L.
Marks, Xiaolei Li, Mark Grinstaff, Conor L. Evans. Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy.
Possible Function of Endothelial Cells as Oxygen Sensors.- Influence of Oxidative Stress on Metabolic and Contractile Functions of Arterial Smooth Muscle.- Free Cytosolic Adenosine Sensitively Signals Myocardial Hypoxia 1.
Annu Rev Physiol. ; Cellular mechanism of oxygen sensing. Lopez-Barneo J(1), Pardal R, Ortega-Sáenz P. Author information: (1)Departamento de Fisiología, Facultad de Medicina y Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Sevilla, E, Spain.
[email protected] O2 sensing is a fundamental biological process necessary for adaptation of living organisms Cited by: Abstract: This book covers a wide biological range of problems regarding oxygen sensing in tissues. Oxygen sensing is defined as a process in which 02 reacts with different cellular components to avoid hypoxic cell damages.
The Lumee Oxygen Platform consists of four components: (1) the Lumee Oxygen hydrogel sensor, (2) the Lumee Pen injector, (3) the Lumee Console, and (4) the Lumee Spotlight readers as well as the associated software. At present, the system has European CE Mark approval for measuring oxygen in subcutaneous tissue.
Available information suggests that when tissue oxygen supply is limited, mitochondria emanate signals involving reactive oxygen species generation which in turn stabilizes oxygen sensing transcription factor HIF Upon stabilization, HIF-1 elicits necessary genetic response to cope with the diminished oxygen Cited by: 8.
Recent developments in the area of biological detection by optical sensing of molecular oxygen (O 2) are reviewed, with particular emphasis on the quenched-phosphorescence O 2 sensing technique.
Following a brief introduction to the main principles, materials and formats of sensor technology, the main groups of applications targeted to biological detection using an O 2 transducer are described. Significant progress has been made in recent years in quenched-phosphorescence oxygen sensing, particularly in the materials and applications of this detection technology that are open to commercialization, like uses in brain imaging and food packaging.
Prompted by this, the editors have delivered a dedicated book that brings together these developments, provides a comprehensive. This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system.
The respiratory system takes oxygen from the atmo-File Size: KB.This led us to hypothesize that the oxygen-sensing PHD proteins might influence T cell differentiation and function, particularly in the oxygen-rich environment of the lung.
Here, we show that T-cell-intrinsic expression of the PHD proteins suppresses pulmonary inflammation against innocuous foreign antigens but powerfully licenses tumor. The platform consists of novel pH sensors (fluorescein based) and oxygen sensors (palladium porphyrin complex based) 1 covalently attached to silica microspheres (10 Cited by: 1.